General Catagory Information : Age Intervention

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Age Intervention Face

Age Intervention Face is a breakthrough in anti-aging technology for adult women. Age Intervention Face addresses the appearance of aging skin changes by targeting two critical areas: hormonal levels and changes associated with cumulative sun exposure.

Declining Sex Hormones in Females

Hormones have a major effect on the brain, bones, the heart, muscle mass and the skin. In females, hormonal levels begin to slowly decline at the age of 25. The average age of peri-menopause is 37 and the average onset of menopause is between 49 and 51 years of age.

The decline of sex hormones is not an even, transitional process for women, but one of constant fluctuations that can manifest itself in many internal changes as well as changes that can affect the appearance of facial skin.

Hormonal decline in males is very gradual, but in females it is a much more obvious and well-defined process. Biologically, this decline is natural. Once the reproductive years are completed, declining hormones are part of the natural aging process. However, in today's society women do not die shortly after the childbearing years, but continue to live healthy productive lives long after they cease to give birth. In the U.S. today there are more females over the age of 40 than ever before in history. The over 40 population will be in the workforce longer than any other generation and will live longer than any other generation. Because of new medical advancements, they will also have a greater opportunity to maintain a youthful, vibrant appearance particularly regarding the appearance of aging and sun-damaged skin.

Hormones and Aging Skin Changes

As females age and hormonal levels drop, the sebaceous glands begin to atrophy contributing to drier skin. In addition, the decline of estrogen results in a reduced moisture content, also exacerbating the formation of fine lines and wrinkles. Other hormonal related changes include:

• Decreased fat content in the skin eventually resulting in less substance and more skeletal facial contours width
• Decreased epidermal cell turnover
• Impaired barrier function resulting in greater transepidermal moisture loss and risk of irritation
• Thinning of the dermis
• Thinner and sparser elastin fibers
• Changes in collagen production and collagen fibers
• Diminished vascularization (blood supply) to the surface of the skin
• Decrease in the skin's immune functions
• Changes in pigment cells

Balanced hormone replacement has been shown to assist in restoring the body to a more youthful state. Many studies demonstrate that topical application of certain combined hormonal substances is more effective in significantly benefiting the appearance of aging facial skin than oral supplementation, without the concern of systemic absorption. Further, a number of studies have established that topical application of hormonal substances appears to specifically benefit facial skin in ways that are more dramatic and measurable than with oral supplementation. Estrogen, in particular, has been shown to visibly improve the quality of skin and restore a more youthful facial appearance. For example, all skin cells have receptors for estrogen. It appears that topical application sends messages to the skin''s cells that may contribute to maintaining more youthful collagen levels along with other critical factors. Studies involving the topical application of certain hormonal combinations have concluded that users experienced greater skin thickness, significant reduction in the appearance of wrinkles, greater skin resiliency, increased barrier function and higher moisture content. The skin also appeared softer, smoother, firmer and more elastic.

Age Intervention Face is comprised of the latest medically based technology designed to target and address female skin changes due to changing hormonal levels. Age Intervention Face will assist in revitalizing and restoring the appearance of youthful suppleness and elasticity by recapturing your skin's normal hormonal balance.

New Advancements in Treating Cumulative Sun Damage

Age Intervention Face establishes a new level of female skin rejuvenation by combining the hormonal component of skin aging with topical agents that can measurably improve the appearance of cumulative sun damage. Cumulative sun exposure is the greatest cause of what most people think of as "inevitable skin aging". Two major factors involved in photo-damaged skin are:

• Impaired immune function that inhibits cells from repairing damage, which then contributes to numerous aging skin changes.
• Inflammatory responses that trigger free radical activity causing cellular damage and cellular abnormalities.

Jan Marini Skin Research has grouped together an extraordinary combination of topical agents that can effectively boost the skin's ability to repair damage and prevent certain inflammatory actions. Some of these key breakthroughs include

• Topical interferon. Interferon is produced by the body and is often referred to as an "immune messenger". Medically, interferon is injected in order to improve survival rates in malignant melanoma, adult leukemia and hepatitis C. It is also used topically on patients who have recalcitrant episodes of warts. Some researchers believe topically applied interferon may significantly reduce the appearance of fine lines and wrinkles associated with cumulative sun damage. It is speculated that interferon appears to have a substantial repair mechanism on compromised cells, enabling them to perform in a younger and healthier manner.
• Repair of DNA. Ultraviolet light can affect DNA and result in potentially cancerous mutation in skin cells. When the body tries to repair this damage, the immune system is monopolized and normal immune activities are affected. A newly identified substance derived from plankton has been shown to repair DNA as it becomes damaged. Scientists have found that a light-sensitive enzyme in algae can reverse cell damage caused by ultraviolet radiation. Studies show that this substance can also inhibit many inflammatory skin reactions.
• CoEnzyme Q10. CoEnzyme Q10 is a vitamin-like nutrient that resides in the mitochondrial cell membrane. It is a major antioxidant and also works to stabilize membrane activity. CoEnzyme Q10 is often referred to as a major “cellular energy source. Worldwide studies confirm the benefits of oral CoEnzyme Q10 supplements. Medical studies also demonstrate that topical application of CoEnzyme Q10 significantly improves the appearance of photo-damaged skin and also helps to protect the skin from additional damage. Reported results show a marked reduction in the appearance of wrinkles, increases in the skin's production of hyaluronic acid, greater organization of collagen fibers and prevention of inflammatory activity.
• Methysulfonylmethane (MSM). MSM is a water-soluble compound found in all living things. MSM is an organic form of sulfur. MSM is considered to have exceptional anti-inflammatory qualities. It is believed that MSM also assists in keeping the bonds between skin cells flexible, prevents cross linking of collagen, enhances collagen production and helps to keep cell walls permeable.
• Barrier Function. As skin ages and is compromised by cumulative sun exposure and hormonal fluctuations, the skin’s integrity and barrier functions are also compromised. Barrier function is integral in preventing trans-epidermal moisture loss, and to limiting skin irritation and inflammation. Without adequate barrier function the skin is far more vulnerable to contact dermatitis, irritation and inflammatory responses. Age Intervention Face incorporates the latest research and technology regarding the repair and maintenance of barrier function.

In conclusion, the overall combined topical agents in Age Intervention Face provide extraordinary skin rejuvenation and maintenance benefits for the appearance of female facial skin.

Age Intervention Hands

It is often said that even if a woman has a youthful appearing face, her hands can give away her age. The hands are indeed a challenging area. Years of constant cumulative sun exposure take its toll in the form of textural changes, discoloration and weathered, dry surface skin. Age Interventionâ Hands is comprised of an intensive combination of acids, lightening agents and anti-inflammatory agents that can dramatically target these common concerns resulting in measurably younger looking hands.

Some of these key topical agents include:

• Glycolic Acid (20%). Glycolic Acid is an excellent resurfacing agent that can effectively improve texture and fine lines, and assist in evening skin tones. Medical studies demonstrate that glycolic acid, formulated at correct ph, can stimulate other substances that are responsible for epidermal volume. In addition, glycolic acid is believed to potentiate the benefit of other active resurfacing agents.
• Azelaic Acid (5%). Azelaic acid is known as a pigment lifting agent that can assist in minimizing or resolving the appearance of brown spots and other aging/sun related discoloration. Azelaic acid is also an exceptional resurfacing agent that can noticeably improve skin texture, fine lines and dryness.
• Salicylic Acid (2%). Salicylic acid is a Beta Hydroxy acid that also acts as an outstanding resurfacing agent that adds further skin smoothing and skin evening benefits.
• Kojic Acid (5%). Kojic acid is a pigment lightening agent used by physicians and skin care professionals to safely minimize and resolve abnormal pigment changes. There is no known toxicity or side effects associated with kojic acid and it can be used indefinitely to clear pigment changes and as well as for continued maintenance. Many physicians and researchers believe that kojic acid is as effective or more effective than some prescription Hydroquinone products.
• CoEnzyme Q10. CoEnzyme Q10 is a vitamin-like nutrient that resides in the mitochondrial cell membrane. It is a major antioxidant and also works to stabilize membrane activity. CoEnzyme Q10 is often referred to as a major cellular energy source. Worldwide studies confirm the benefits of oral CoEnzyme Q10 supplements. Medical studies also demonstrate that topical application of CoEnzyme Q10 significantly improves the appearance of photo-damaged skin and also helps to protect the skin from additional damage. Reported results show a marked reduction in the appearance of wrinkles, increases in the skin's production of hyaluronic acid, greater organization of collagen fibers and prevention of inflammatory activity.
• Methysulfonylmethane (MSM). MSM is a water-soluble compound found in all living things. MSM is an organic form of sulfur. MSM is considered to have exceptional anti-inflammatory qualities. It is believed that MSM also assists in keeping the bonds between skin cells flexible, prevents cross linking of collagen, enhances collagen production and helps to keep cell walls permeable. Some researchers believe that topical MSM may also reduce and prevent brown spots and other age related skin changes.
• Parsol 1789. Parsol 1789 is a full spectrum sunscreen that in combination with other sunscreens blocks both UVB and UVA rays. Daily continuous use of sunscreen is critical to maintaining visible improvement and to prevent future damage.

Used twice daily, Age Intervention Hands will resurface hands, resulting in dramatically younger looking, smoother and more even-toned skin.